Pa Epulo 15, 2022, kupanga kwa mphete yayikulu ya Lecardipine hydrochloride kunamalizidwa nthawi imodzi, ndipo mphamvu yopangira pano ndi 5Mt / mwezi.
Dzina la Chingerezi:Lercanidipine hydrochloride
Dzina la Chemical:1,4-Dihydro-2,6-dimethyl-4- (3-nitrophenyl) -3,5-pyridinedicarboxylic acid 2--[(3,3-di phenylpropyl)methylamino]-l,l-dimethylethyl methyl ester hydrochloride.
Nambala ya CAS: 132866-11-6
Ntchito:Pochiza mankhwala a Lecardipine hydrochloride, sizikhala ndi zotsatira zoyipa pamagazi a shuga ndi lipids, ndipo zimakhala ndi antihypertensive kwenikweni.
Chiyembekezo cha msika:
Ku China kuli odwala matenda oopsa opitirira 200 miliyoni, ndipo pali odwala 10 miliyoni atsopano omwe ali ndi vuto la kuthamanga kwa magazi chaka chilichonse, omwe ambiri mwa iwo sakuwongolera, zomwe zimapangitsa kuti pakhale vuto lalikulu la matenda oopsa monga sitiroko, komanso kufa pachaka ku China Pakati pa 3. odwala miliyoni omwe ali ndi matenda amtima, 50% amakhudzana ndi matenda oopsa, ndipo mtengo wapachaka wa chithandizo chamankhwala amtima ndi pafupifupi 309.8 biliyoni ya yuan.Chifukwa cha kuwongolera koyipa sikuli kokha kuti kuzindikira kwa odwala matenda a kuthamanga kwa magazi ndi zovuta zake kuyenera kuwongolera, komanso kuti odwala ambiri omwe amafunikira kumwa mankhwala kwa moyo wawo wonse samatsatira bwino ndipo sangathe kumwa mankhwala tsiku lililonse Komabe, izi zikuwonetsanso kuti Msika wa mankhwala a antihypertensive uli ndi mwayi wokulirakulira.Poyerekeza ndi mankhwala ofanana, locarbodipine hydrochloride ali amphamvu mtima kusankha.Katundu wake wapadera wa lipophilic umapangitsa kuti ikhale yocheperako komanso yokhalitsa antihypertensive zotsatira Mphamvu ya atherogenic, makamaka yoyenera kwa odwala matenda oopsa omwe ali ndi atherosulinosis, imakhala ndi phindu lalikulu lachipatala komanso chiyembekezo chachikulu chamsika.
Pharmacological zochita:
Lecardipine ndi mbadwo watsopano wa dihydropyridine kashiamu njira gulu hysteresis wothandizila, ndi amphamvu mtima kusankha, wofatsa tingati, amphamvu antihypertensive tingati, nthawi yaitali kanthu, zochepa zoipa inotropic kwenikweni ndi zina zotero.Maphunziro a m'galasi apeza kuti locarbodipine imakhudza mwachindunji minofu yosalala ya mitsempha, choncho imakhala ndi mphamvu ya antihypertensive mu vivo, koma imakhala ndi zotsatira zochepa pa kugunda kwa mtima ndi mtima.Chifukwa cha jini yake yayikulu ya hydrophobic komanso kusungunuka kwamphamvu kwa lipid, locarbodipine imagawidwa mwachangu ku minofu ndi ziwalo pambuyo polowa m'thupi, kumangiriza kwambiri ku nembanemba yosalala ya minofu, ndikutulutsa pang'onopang'ono.Choncho, ngakhale seramu ya mankhwalawa imakhala ndi nthawi yochepa yochotseratu kulephera kwa theka, zotsatira zake zimakhala zotalika.
Nthawi yotumiza: Apr-15-2022